Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SI | P14410 | 1/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | S100A4 | P26447 | 2/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16937116 | 0.89 | TDP1 (0.57) | TDP1ALDH1A1PDE7ASMN1; SMN2MGAM | |
| SCHEMBL2947942 | 0.86 | TDP1 (0.59) | TDP1ALDH1A1PDE7ASMN1; SMN2MGAM | |
| SCHEMBL28582831 | 0.86 | GPR35 (0.49) | TDP1ALDH1A1PDE7ASMN1; SMN2MGAM | |
| SCHEMBL29337154 | 0.85 | ALDH1A1 (0.57) | TDP1ALDH1A1PDE7ASMN1; SMN2MGAM | |
| SCHEMBL24548 | 0.82 | TDP1 (0.60) | TDP1ALDH1A1PDE7ASMN1; SMN2GAA | |
| SCHEMBL29448254 | 0.82 | TDP1 (0.60) | TDP1ALDH1A1PDE7ASMN1; SMN2GAA | |
| SCHEMBL8519148 | 0.82 | S100A4 (0.55) | TDP1ALDH1A1PDE7ASMN1; SMN2MGAM | |
| SCHEMBL1287837 | 0.82 | ALDH1A1 (0.74) | TDP1ALDH1A1MGAMGAASI | |
| SCHEMBL30535903 | 0.82 | ALDH1A1 (0.74) | TDP1ALDH1A1MGAMGAASI | |
| SCHEMBL15801775 | 0.81 | ALDH1A1 (0.49) | TDP1ALDH1A1PDE7ASMN1; SMN2MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563118-A | FORMING GRAFT POLYMER BY REACTING ETHYLENE-ALPHA OLEFIN POLYMER WITH CARBOXYLIC ACID ACYLATING AGENT AND NITROPHENYL PHENYLENEDIAMINE COMPOUND | DSM COPOLYMER, INC. (US) | 1996-10-08 | — | — | US | claimed |
| US-5429757-A | ADDITIVE WHICH IMPROVES VISCOSITY INDEX AND IS A DISPERSANT AND AN ANTIOXIDANT IN LUBRICANTS | TEXACO INC. (US) | 1995-07-04 | — | — | US | claimed |
| US-5563118-A | FORMING GRAFT POLYMER BY REACTING ETHYLENE-ALPHA OLEFIN POLYMER WITH CARBOXYLIC ACID ACYLATING AGENT AND NITROPHENYL PHENYLENEDIAMINE COMPOUND | DSM COPOLYMER, INC. (US) | 1996-10-08 | — | — | US | disclosed |
| US-5429757-A | ADDITIVE WHICH IMPROVES VISCOSITY INDEX AND IS A DISPERSANT AND AN ANTIOXIDANT IN LUBRICANTS | TEXACO INC. (US) | 1995-07-04 | — | — | US | disclosed |
| EP-0391264-A1 | Reactive dyes with two or three halogen-N-heterocycles as reactive groups | BASF Aktiengesellschaft (DE) | 1990-10-10 | — | — | EP | disclosed |