Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
| ▸ | CYP2A13 | Q16696 | 3/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL793723 | 0.89 | HRH3 (0.52) | HRH3MAPTNCF1SMN1; SMN2JAK2 | |
| SCHEMBL793450 | 0.89 | HRH3 (0.56) | HRH3MAPTCYP1A2CYP2D6NCF1 | |
| SCHEMBL29632675 | 0.81 | NCF1 (0.45) | HRH3MAPTNCF1SMN1; SMN2JAK2 | |
| SCHEMBL20908819 | 0.81 | CNR2 (0.51) | HRH3MAPTNCF1SMN1; SMN2CXCR4 | |
| SCHEMBL31703161 | 0.78 | NCF1 (0.42) | HRH3MAPTNCF1SMN1; SMN2JAK2 | |
| SCHEMBL31703257 | 0.78 | HRH3 (0.45) | HRH3MAPTNCF1SMN1; SMN2CXCR4 | |
| SCHEMBL19229780 | 0.75 | SMN1; SMN2 (0.51) | HRH3MAPTCYP1A2CYP2D6NCF1 | |
| SCHEMBL6033570 | 0.75 | CXCR4 (0.49) | HRH3MAPTCYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL797884 | 0.75 | GAA (0.47) | SMN1; SMN2CYP2A13KDM4ETSHRALDH1A1 | |
| SCHEMBL797883 | 0.75 | GAA (0.47) | SMN1; SMN2CYP2A13KDM4ETSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4112617-A1 | METHOD FOR PREPARATION OF HETEROCYCLICAMINE DERIVATIVES | Daewoong Pharmaceutical Co., Ltd. (KR) | 2023-01-04 | — | — | EP | disclosed |
| WO-2012035055-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012035055-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-22 | — | — | WO | disclosed |
| WO-2011110575-A1 | DERIVATIVES OF 2-[2-(BENZO- OR PYRIDO-) THIAZOLYLAMINO]-6-AMINOPYRIDINE, USEFUL IN THE TREATMENT OF RESPIRATORIC, ALLERGIC OR INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2011-09-15 | — | — | WO | disclosed |