Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA6 | P23280 | 5/20 | 0.50 |
| ▸ | CA7 | P43166 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA4 | P22748 | 4/20 | 0.50 |
| ▸ | CA5A | P35218 | 4/20 | 0.50 |
| ▸ | CA3 | P07451 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | F13A1 | P00488 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | THPO | P40225 | 2/20 | 0.48 |
| ▸ | CASP2 | P42575 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981161 | 0.93 | CA12 (0.52) | CA12CA6CA7CA9CA14 | |
| SCHEMBL7971206 | 0.85 | CA12 (0.53) | CA12CA6CA7CA9CA14 | |
| SCHEMBL16552936 | 0.83 | CA12 (0.55) | CA12CA6CA7CA9CA14 | |
| SCHEMBL8699212 | 0.79 | CA12 (0.59) | CA12CA6CA7CA9CA14 | |
| SCHEMBL9111058 | 0.79 | ENPEP (0.38) | ALDH1A1 | |
| SCHEMBL28352525 | 0.79 | ALDH1A1 (0.52) | TSHRALDH1A1 | |
| SCHEMBL1460229 | 0.79 | ALDH1A1 (0.52) | TSHRALDH1A1 | |
| SCHEMBL4826284 | 0.79 | ANPEP (0.37) | CA12CA6CA7CA9CA14 | |
| SCHEMBL351351 | 0.76 | — | — | |
| SCHEMBL4809727 | 0.76 | CA12 (0.37) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300340-B1 | USEFUL FOR THERAPY OF CANCER AND SOLID TUMORS | ADIR ET COMPAGNIE (FR) | 2001-10-09 | — | — | US | disclosed |
| US-6162822-A | Bisimide compounds | ADIR ET COMPAGNIE (FR) | 2000-12-19 | — | — | US | disclosed |
| EP-0820985-B1 | Bis imide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-08-30 | — | — | EP | disclosed |
| US-5854273-A | Bisimide compounds | ADIR ET COMPAGNIE (FR) | 1998-12-29 | — | — | US | disclosed |
| EP-0820985-A1 | Bis imide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-01-28 | — | — | EP | disclosed |