Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982464 | 0.83 | MEN1 (0.47) | TSHRMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL26186404 | 0.82 | OPRD1 (0.48) | TSHRMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL7985481 | 0.81 | POLQ (0.41) | TSHRMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7968760 | 0.81 | MEN1 (0.58) | TSHRMEN1KMT2ANPSR1KDM4E | |
| SCHEMBL26186679 | 0.81 | KMT2A (0.41) | TSHRMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL7978952 | 0.79 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1NPSR1NPC1 | |
| SCHEMBL26186365 | 0.79 | P2RX4 (0.43) | TSHRMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL30285727 | 0.79 | NPC1 (0.40) | KMT2AALDH1A1NPC1RAB9AMAPK14 | |
| SCHEMBL26186409 | 0.79 | NPC1 (0.40) | KMT2AALDH1A1NPC1RAB9AMAPK14 | |
| SCHEMBL19512684 | 0.79 | NPSR1 (0.47) | TSHRMEN1KMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| CN-1252068-A | 3-piperidyl-4-oxoquinazoline derivatives and pharmaceutical compositions containing the same | JAPAN TOBACCO INC (JP) | 2000-05-03 | — | — | CN | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |