Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 12/20 | 0.67 |
| ▸ | ACHE | P22303 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.63 |
| ▸ | HRH2 | P25021 | 1/20 | 0.63 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.63 |
| ▸ | HTR2A | P28223 | 1/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.63 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4556566 | 0.89 | MAPK1 (0.68) | BCHEACHEMAPK1ADRB3HRH2 | |
| SCHEMBL8970221 | 0.87 | MAPK1 (0.67) | BCHEACHEMAPK1ADRB3HRH2 | |
| SCHEMBL627575 | 0.86 | BCHE (0.65) | BCHEACHEMAPK1NOX1NPSR1 | |
| SCHEMBL6313879 | 0.83 | BCHE (0.65) | BCHEACHEMAPK1ADRB3HRH2 | |
| SCHEMBL11618894 | 0.83 | BCHE (0.67) | BCHEACHEMAPK1ADRB3HRH2 | |
| SCHEMBL20272375 | 0.83 | BCHE (0.71) | BCHEACHEMAPK1ADRB3HRH2 | |
| SCHEMBL20272371 | 0.82 | BCHE (0.61) | BCHEACHEMAPK1ADRB3HRH2 | |
| Hydrochloric Acid SCHEMBL5499595 | 0.82 | BCHE (0.66) | BCHEACHEMAPK1ADRB3HRH2 | |
| SCHEMBL8428979 | 0.80 | MAPK1 (0.70) | BCHEACHEMAPK1ADRB3HRH2 | |
| SCHEMBL7350072 | 0.79 | BCHE (0.63) | BCHEACHEHRH2HTR2ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001092240-A1 | NOVEL N-SUBSTITUTED PHENOTHIAZINES AND THEIR USE AS MODULATORS OF SERINE HYDROLASE ENZYMES | DALHOUSIE UNIVERSITY (CA) | 2001-12-06 | — | — | WO | disclosed |