SCHEMBL8970221

SCHEMBL8970221

CCCCCCCCCCCCCCCCCC(=O)N1c2ccccc2Sc2ccccc21

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.67
BCHE P06276 12/20 0.65
ADRB3 P13945 1/20 0.65
HRH2 P25021 1/20 0.65
ADRA1D P25100 1/20 0.65
HTR2A P28223 1/20 0.65
SLC6A4 P31645 1/20 0.65
SLC6A3 Q01959 1/20 0.65
ACHE P22303 2/20 0.60
GFER P55789 1/20 0.59
NPSR1 Q6W5P4 1/20 0.55
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
NOX1 Q9Y5S8 1/20 0.54
GAA P10253 1/20 0.54
MAPT P10636 1/20 0.54
POLB P06746 1/20 0.54
ATM Q13315 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4556566 0.98 MAPK1 (0.68) MAPK1BCHEADRB3HRH2ADRA1D
SCHEMBL7982855 0.87 BCHE (0.67) MAPK1BCHEADRB3HRH2ADRA1D
SCHEMBL8428979 0.81 MAPK1 (0.70) MAPK1BCHEADRB3HRH2ADRA1D
SCHEMBL6313879 0.78 BCHE (0.65) MAPK1BCHEADRB3HRH2ADRA1D
SCHEMBL20272375 0.78 BCHE (0.71) MAPK1BCHEADRB3HRH2ADRA1D
SCHEMBL11618894 0.78 BCHE (0.67) MAPK1BCHEADRB3HRH2ADRA1D
SCHEMBL20272371 0.77 BCHE (0.61) MAPK1BCHEADRB3HRH2ADRA1D
Hydrochloric Acid SCHEMBL5499595 0.77 BCHE (0.66) MAPK1BCHEADRB3HRH2ADRA1D
SCHEMBL11152974 0.75 MAPK1 (0.58) MAPK1BCHEADRB3HRH2ADRA1D
SCHEMBL17022631 0.75 NOTUM (0.60) MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5543448-A CONTAINING A BLOCK ADDITION POLYMER THE DOW CHEMICAL COMPANY (US) 1996-08-06 US disclosed
US-5539030-A POLYMER BLENDS FOR MOLDING MATERIALS THE DOW CHEMICAL COMPANY (US) 1996-07-23 US disclosed
US-5525651-A CONTAINS EPOXY RESIN, STYRENIC COPOLYMER, AND ANTIMONY COMPOUND; IMPACT STRENGTH, HEAT RESISTANCE THE DOW CHEMICAL COMPANY (US) 1996-06-11 US disclosed
US-5424341-A A molding material comprising a styrenic copolymer amd epoxy resins; impact and ignition resistance, heat resistance, paintability; films, sheets, instrumentral panels, housings and parts for electronics, automobiles THE DOW CHEMICAL COMPANY (US) 1995-06-13 US disclosed
US-5416148-A Balance of impact and solvent resistance; films, fibers, extruded sheets, laminates, moldings, automobile body panels THE DOW CHEMICAL COMPANY (US) 1995-05-16 US disclosed
EP-0630392-A1 POLYMERS AND POLYMER BLENDS MODIFIED WITH POLY(PHENYLENE ETHER) THE DOW CHEMICAL COMPANY (US) 1994-12-28 EP disclosed
WO-1994011429-A1 IGNITION RESISTANT POLYCARBONATE BLENDS THE DOW CHEMICAL COMPANY (US) 1994-05-26 WO disclosed
US-5286790-A Blends; melting, molding; polycarbonates, styrene-maleic anhydride graft polymers THE DOW CHEMICAL COMPANY (US) 1994-02-15 US disclosed
US-5270386-A Styrenic copolymers modified with poly (phenylene ether) THE DOW CHEMICAL COMPANY (US) 1993-12-14 US disclosed
US-5262476-A Hydrogenated block or graft copolymers from vinylaromatic and glycidyl methacrylate THE DOW CHEMICAL COMPANY (US) 1993-11-16 US disclosed
US-5258432-A Polyester, (meth)acrylate homopolymer, polytetrafluoroethylene, organophosphorus compound and an aromatic halogenated carbonate oligomer THE DOW CHEMICAL COMPANY (US) 1993-11-02 US disclosed
WO-1993019128-A2 POLYMERS AND POLYMER BLENDS MODIFIED WITH POLY(PHENYLENE ETHER) THE DOW CHEMICAL COMPANY (US) 1993-09-30 WO disclosed
WO-1993018090-A1 IGNITION RESISTANT POLYCARBONATE BLENDS THE DOW CHEMICAL COMPANY (US) 1993-09-16 WO disclosed