Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 10/20 | 0.65 |
| ▸ | ACHE | P22303 | 4/20 | 0.64 |
| ▸ | HRH2 | P25021 | 2/20 | 0.62 |
| ▸ | HTR2A | P28223 | 2/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.62 |
| ▸ | HTR1D | P28221 | 1/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | HTR3A | P46098 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5499595 | 0.99 | BCHE (0.66) | BCHEACHEHRH2HTR2ASLC6A3 | |
| Chloracyzine SCHEMBL30719025 | 0.89 | ALDH1A1 (0.77) | BCHEACHEHRH2HTR2ASLC6A3 | |
| Chloracyzine SCHEMBL309939 | 0.89 | ALDH1A1 (0.77) | BCHEACHEHRH2HTR2ASLC6A3 | |
| Chloracyzine SCHEMBL29388455 | 0.89 | ALDH1A1 (0.77) | BCHEACHEHRH2HTR2ASLC6A3 | |
| Chloracyzine SCHEMBL11614590 | 0.88 | ALDH1A1 (0.79) | BCHEACHEHRH2HTR2ASLC6A3 | |
| Chloracyzine SCHEMBL1650585 | 0.87 | ALDH1A1 (0.74) | BCHEACHEHRH2HTR2ASLC6A3 | |
| Fluacizine SCHEMBL29388364 | 0.86 | MEN1 (0.61) | BCHEACHESLC6A3CHRM2HTR1A | |
| Fluacizine SCHEMBL49497 | 0.86 | MEN1 (0.61) | BCHEACHESLC6A3CHRM2HTR1A | |
| SCHEMBL7350072 | 0.85 | BCHE (0.63) | BCHEACHEHRH2HTR2ASLC6A3 | |
| Fluacizine SCHEMBL1650048 | 0.84 | MEN1 (0.59) | BCHEACHESLC6A3CHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10940150-B2 | Thymine derivatives and quinazoline-dione derivatives for the inhibition of HSP27 | TECHNISCHE UNIVERSITAET DRESDEN (DE) | 2021-03-09 | — | — | US | disclosed |
| US-20180207160-A1 | THYMINE DERIVATIVES AND QUINAZOLINE-DIONE DERIVATIVES FOR THE INHIBITION OF HSP27 | TECHNISCHE UNIVERSITAET DRESDEN (DE) | 2018-07-26 | — | — | US | disclosed |
| US-20170216297-A1 | EFFICIENT INHIBITION OF HSP27 | TECHNISCHE UNIVERSITAET DRESDEN (DE) | 2017-08-03 | — | — | US | disclosed |
| US-20170216297-A1 | EFFICIENT INHIBITION OF HSP27 | TECHNISCHE UNIVERSITAET DRESDEN (DE) | 2017-08-03 | — | — | US | disclosed |
| US-6916661-B2 | Microparticles with multiple fluorescent signals and methods of using same | LUMINEX CORPORATION (US) | 2005-07-12 | — | — | US | disclosed |
| US-20040087032-A1 | Microparticles with multiple fluorescent signals and methods of using same | CHANDLER MARK B (US) | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180207160-A1 | THYMINE DERIVATIVES AND QUINAZOLINE-DIONE DERIVATIVES FOR THE INHIBITION OF HSP27 | HSPB1, HSP90B1, HSP90AB1 | BCHE 4761/4885ACHE 4544/4885HRH2 657/4885 |
| US-20170216297-A1 | EFFICIENT INHIBITION OF HSP27 | HSPB1, HSP90AB2P, HSP90B1 | BCHE 4854/4885ACHE 4859/4885HRH2 275/4885 |
| US-10940150-B2 | Thymine derivatives and quinazoline-dione derivatives for the inhibition of HSP27 | HSPB1, HSP90B1, HSP90AB1 | BCHE 4761/4885ACHE 4544/4885HRH2 657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.