Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993062 | 0.84 | MAPK14 (0.50) | KDM4ELMNASMN1; SMN2RAB9AADORA2A | |
| SCHEMBL8000327 | 0.84 | MAPK14 (0.57) | ADORA2AADORA1MAPK14MAPK13MAPK12 | |
| SCHEMBL7996121 | 0.84 | MAPK14 (0.53) | TDP1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL22898800 | 0.78 | TDP1 (0.66) | TDP1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL28453044 | 0.78 | KDM4E (0.56) | TDP1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7997046 | 0.75 | MAPK11 (0.54) | ADORA2AADORA1MAPK14MAPK13MAPK12 | |
| SCHEMBL12339141 | 0.72 | RAB9A (0.58) | TDP1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7983814 | 0.72 | MAPK14 (0.57) | TDP1NPC1RAB9AADORA2AADORA1 | |
| SCHEMBL13727890 | 0.71 | TDP1 (0.72) | TDP1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL13726202 | 0.71 | TDP1 (0.60) | TDP1ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001057018-A1 | AZAAZULENE INHIBITORS OF P38 MAP KINASE AND TNF-ALPHA | ABBOTT LABORATORIES (US) | 2001-08-09 | — | — | WO | claimed |
| WO-2001057018-A1 | AZAAZULENE INHIBITORS OF P38 MAP KINASE AND TNF-ALPHA | ABBOTT LABORATORIES (US) | 2001-08-09 | — | — | WO | disclosed |