Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 12/20 | 0.77 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | TLR4 | O00206 | 4/20 | 0.52 |
| ▸ | TLR2 | O60603 | 4/20 | 0.52 |
| ▸ | VCP | P55072 | 2/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL527535 | 0.88 | FBP1 (1.00) | FBP1MAOAMAOBTLR4TLR2 | |
| SCHEMBL527534 | 0.88 | FBP1 (1.00) | FBP1MAOAMAOBTLR4TLR2 | |
| (2-Nitrovinyl)Benzene SCHEMBL8574134 | 0.82 | FBP1 (0.72) | FBP1MAOAMAOBTLR4TLR2 | |
| Diethylamine SCHEMBL9301198 | 0.78 | NFE2L2 (0.50) | FBP1MAOAMAOBNFE2L2 | |
| SCHEMBL5211010 | 0.73 | FBP1 (0.85) | FBP1MAOAMAOBTLR4TLR2 | |
| SCHEMBL30995730 | 0.72 | FBP1 (1.00) | FBP1MAOAMAOBTLR4TLR2 | |
| SCHEMBL1027331 | 0.72 | FBP1 (1.00) | FBP1MAOAMAOBTLR4TLR2 | |
| SCHEMBL1027330 | 0.72 | FBP1 (1.00) | FBP1MAOAMAOBTLR4TLR2 | |
| SCHEMBL2285894 | 0.70 | FBP1 (0.67) | FBP1VCP | |
| SCHEMBL2285892 | 0.70 | FBP1 (0.67) | FBP1VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6280884-B1 | HOLOGRAPHIC STORAGE IN PHOTOREFRACTIVE POLYMERIC OPTICAL ARTICLE, EXPOSURE TO ELECTROMAGNETIC RADIATION WITH INTERSECTING BEAMS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2001-08-28 | — | — | US | claimed |
| US-6280884-B1 | HOLOGRAPHIC STORAGE IN PHOTOREFRACTIVE POLYMERIC OPTICAL ARTICLE, EXPOSURE TO ELECTROMAGNETIC RADIATION WITH INTERSECTING BEAMS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2001-08-28 | — | — | US | disclosed |
| US-5361148-A | Apparatus for photorefractive two beam coupling | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1994-11-01 | — | — | US | disclosed |