SCHEMBL527535

SCHEMBL527535

O=[N+]([O-])C=Cc1cccc(F)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 13/20 1.00
VCP P55072 2/20 0.64
MAOA P21397 2/20 0.63
MAOB P27338 2/20 0.63
NFE2L2 Q16236 3/20 0.61
TLR4 O00206 2/20 0.57
TLR2 O60603 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL527534 1.00 FBP1 (1.00) FBP1VCPMAOAMAOBNFE2L2
Diethylamine SCHEMBL7982944 0.88 FBP1 (0.77) FBP1VCPMAOAMAOBNFE2L2
SCHEMBL2285892 0.80 FBP1 (0.67) FBP1VCP
SCHEMBL2285894 0.80 FBP1 (0.67) FBP1VCP
SCHEMBL5211010 0.79 FBP1 (0.85) FBP1VCPMAOAMAOBTLR4
SCHEMBL1027330 0.78 FBP1 (1.00) FBP1VCPMAOAMAOBTLR4
SCHEMBL1937312 0.78 FBP1 (1.00) FBP1VCPMAOAMAOBTLR4
SCHEMBL12720865 0.78 FBP1 (1.00) FBP1VCPMAOAMAOBTLR4
SCHEMBL1027331 0.78 FBP1 (1.00) FBP1VCPMAOAMAOBTLR4
SCHEMBL8625803 0.78 FBP1 (1.00) FBP1VCPMAOBNFE2L2TLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119678922-A Application of nitrostyrenes compound in preventing, controlling or resisting plant pathogenic nematodes and preparation thereof 广西田园生化股份有限公司 2025-03-25 CN claimed
CN-118844436-A Application of nitrostyrene compound in preventing and treating plant diseases and food-borne pathogenic bacteria 广西田园生化股份有限公司 2024-10-29 CN claimed
CN-111116613-B Polysubstituted benzimidazole thiazole and derivative and synthesis method thereof 湘潭大学 2021-04-23 CN claimed
US-12612411-B1 Imidazopyrazine derivatives, process for preparation thereof, and their uses as luciferins INSTITUT PASTEUR (FR) 2026-04-28 US disclosed
US-12576164-B2 Imidazopyrazine derivatives, process for preparation thereof, and their uses as luciferins INSTITUT PASTEUR (FR) 2026-03-17 US disclosed
EP-4627896-A2 3D/2D PEROVSKITE SOLAR CELLS ODTÜ-GÜNAM (TR) 2025-10-08 EP disclosed
CN-119678922-A Application of nitrostyrenes compound in preventing, controlling or resisting plant pathogenic nematodes and preparation thereof 广西田园生化股份有限公司 2025-03-25 CN disclosed
CN-119678922-A Application of nitrostyrenes compound in preventing, controlling or resisting plant pathogenic nematodes and preparation thereof 广西田园生化股份有限公司 2025-03-25 CN disclosed
CN-118844436-A Application of nitrostyrene compound in preventing and treating plant diseases and food-borne pathogenic bacteria 广西田园生化股份有限公司 2024-10-29 CN disclosed
CN-118844436-A Application of nitrostyrene compound in preventing and treating plant diseases and food-borne pathogenic bacteria 广西田园生化股份有限公司 2024-10-29 CN disclosed
EP-3964501-B1 IMIDAZOPYRAZINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND THEIR USES AS LUCIFERINS PASTEUR INSTITUT (FR) 2024-09-04 EP disclosed
EP-1944306-A1 Fused heterocyclic compounds as serotonin receptor modulators Janssen Pharmaceutica, N.V. (BE) 2008-07-16 EP disclosed
US-20080103132-A1 FUSED HETEROCYCLIC COMPOUNDS JANSSEN PHARMACEUTICA NV (BE) 2008-05-01 US disclosed
EP-1905774-A1 Fused heterocyclic compounds as serotonin receptor modulators Janssen Pharmaceutica, N.V. (BE) 2008-04-02 EP disclosed
US-20070244328-A1 Organocatalysts and Methods of Use in Chemical Synthesis STC.UNM (US) 2007-10-18 US disclosed
CN-101048393-A Substituted N-arylsulfonyl heterocyclic amines as gamma-secretase inhibitors SCHERING CORP (US) 2007-10-03 CN disclosed
CN-1882590-A Fused heterocyclic compounds as serotonin receptor modulators JOHNSON & JOHNSON (BE) 2006-12-20 CN disclosed
EP-1668014-A2 FUSED HETEROCYCLIC COMPOUNDS AS SEROTONIN RECEPTOR MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2006-06-14 EP disclosed
US-20050119295-A1 Fused heterocyclic compounds JANSSEN PHARMACEUTICA, N.V. (BE) 2005-06-02 US disclosed
WO-2005040169-A2 FUSED HETEROCYCLIC COMPOUNDS AS SEROTONIN RECEPTOR MODULATORS JANSSEN PHARMACEUTICA, N.V. (BE) 2005-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12576164-B2 Imidazopyrazine derivatives, process for preparation thereof, and their uses as luciferins LUC7L2, HLCS, LANCL1 FBP1 1407/4885VCP 4294/4885MAOA 868/4885
US-20070244328-A1 Organocatalysts and Methods of Use in Chemical Synthesis SCO2, CBR1, CBR3 FBP1 3079/4885VCP 4353/4885MAOA 507/4885
US-20050119295-A1 Fused heterocyclic compounds TPH1, HTR3A, HTR3B FBP1 1093/4885VCP 4173/4885MAOA 28/4885
US-12612411-B1 Imidazopyrazine derivatives, process for preparation thereof, and their uses as luciferins LUC7L2, MRPL21, CRY1 FBP1 794/4885VCP 3713/4885MAOA 1257/4885
US-20080103132-A1 FUSED HETEROCYCLIC COMPOUNDS TPH1, HTR3A, HTR3B FBP1 1093/4885VCP 4173/4885MAOA 28/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.