Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847074 | 0.95 | ACE2 (0.43) | ACE2ALDH1A1GPR84FFAR1SLC1A2 | |
| SCHEMBL7718052 | 0.89 | CHRM1 (0.40) | CA2MAPK1ACE2ALDH1A1GPR84 | |
| SCHEMBL7989232 | 0.89 | CHRM1 (0.40) | CA2MAPK1ACE2ALDH1A1GPR84 | |
| SCHEMBL8847217 | 0.83 | GRIK1 (0.42) | CA2MAPK1ACE2ALDH1A1GPR84 | |
| SCHEMBL8421695 | 0.81 | CA2 (0.50) | CA2MAPK1ACE2ALDH1A1GPR84 | |
| SCHEMBL4470713 | 0.79 | CA2 (0.54) | CA2MAPK1ACE2ALDH1A1GPR84 | |
| SCHEMBL6431145 | 0.79 | CA2 (0.54) | CA2MAPK1ACE2ALDH1A1GPR84 | |
| SCHEMBL28570001 | 0.79 | CA2 (0.48) | CA2MAPK1ACE2ALDH1A1GPR84 | |
| SCHEMBL27610235 | 0.77 | ALDH1A1 (0.54) | CA2MAPK1ACE2ALDH1A1GPR84 | |
| SCHEMBL2566459 | 0.76 | GPR84 (0.53) | CA2MAPK1ACE2ALDH1A1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274624-B1 | COMPOUNDS SUCH AS 2-N-PENTYL-4-PENTYNOIC ACID AS ANTIMITOTIC AGENTS | AMERICAN BIOGENETIC SCIENCES INC. | 2001-08-14 | — | — | US | claimed |