SCHEMBL337227

SCHEMBL337227

NC(=O)N(c1ccc(Cl)cc1)c1ccc(Cl)c(Cl)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.42
EPHX1 P07099 2/20 0.42
EPHX2 P34913 2/20 0.42
LMNA P02545 2/20 0.42
MEN1 O00255 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
CHRM1 P11229 1/20 0.42
SLC6A2 P23975 1/20 0.42
PDE4A P27815 1/20 0.42
ADRA1A P35348 1/20 0.42
OPRM1 P35372 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
PDE3A Q14432 1/20 0.42
NLRP3 Q96P20 1/20 0.42
TP53 P04637 2/20 0.40
NPSR1 Q6W5P4 1/20 0.38
CYP3A4 P08684 2/20 0.37
TSHR P16473 1/20 0.37
FLT1 P17948 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29504742 1.00 NPC1 (0.42) NPC1EPHX1EPHX2LMNAMEN1
SCHEMBL7983114 0.93 TSHR (0.42) EPHX1EPHX2MEN1KMT2ANPSR1
SCHEMBL4587677 0.87 NPC1 (0.45) NPC1LMNAHTTNPSR1TSHR
Hydrochloric Acid SCHEMBL27958928 0.85 LMNA (0.46) NPC1LMNANPSR1CYP3A4TSHR
SCHEMBL1525499 0.81 HTR3E (0.44) LMNAMEN1HTTKMT2ATP53
SCHEMBL30019653 0.81 HTR3E (0.44) LMNAMEN1HTTKMT2ATP53
SCHEMBL1879907 0.81 ALDH1A1 (0.42) NPC1EPHX1EPHX2LMNAMEN1
SCHEMBL4588620 0.81 HTR3E (0.47) NPC1LMNAMEN1HTTKMT2A
SCHEMBL4353102 0.80 HSD17B10 (0.41) LMNAMEN1HTTKMT2ACYP3A4
SCHEMBL28834471 0.79 MEN1 (0.44) NPC1LMNAMEN1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 479 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117229856-A Liquid detergent composition and preparation method thereof 纳爱斯浙江科技有限公司 2023-12-15 CN claimed
CN-116615172-A Composition comprising a natural polymer and one or more (bio) alkanediols 西姆莱斯股份公司 2023-08-18 CN claimed
CN-116583261-A Method for combating microorganisms using menthol derivatives 西姆莱斯股份公司 2023-08-11 CN claimed
CN-111631216-A Antimicrobial compositions 西姆莱斯股份公司 2020-09-08 CN claimed
CN-105025712-B Antimicrobial compositions 西姆莱斯股份公司 2020-05-05 CN claimed
CN-110693754-A Antibacterial and anti-inflammatory pyridone composition and cosmetic containing same 烟台东方化学有限公司 2020-01-17 CN claimed
CN-110664633-A Anticorrosion synergistic composition and application thereof 烟台东方化学有限公司 2020-01-10 CN claimed
CN-109475120-A Antimicrobial compositions 西姆莱斯股份公司 2019-03-15 CN claimed
EP-2356977-B1 Preparations with wood extracts of Gleditsia SYMRISE AG (DE) 2017-12-27 EP claimed
EP-2538781-B1 PROCESS FOR THE CO-ENCAPSULATION OF BIOCIDALLY ACTIVE COMPOUNDS IN CLAY MINERALS FUNCTIONALIZED BY NITROGEN COMPOUNDS CLARIANT SA (BR) 2016-08-03 EP claimed
US-20110028545-A1 PROCESS FOR INCORPORATING ANTIMICROBIAL PRODUCTS INTO SOAP COMPOSITIONS LANXESS DEUTSCHLAND GMBH (DE) 2011-02-03 US claimed
US-6998049-B1 Method for preventing the formation of biological films HENKEL ECOLAB GMBH & CO. OHG (DE) 2006-02-14 US claimed
US-6962897-B2 Fluorine-containing lubricants ECOLAB INC. (US) 2005-11-08 US claimed
US-6809068-B1 FOR CHAIN CONVEYOR BELTS AND BOTTLES TRANSPORTED THEREON; ECOLAB INC. 2004-10-26 US claimed
EP-1233749-B1 HAND WASHING LOTION FOR A REFILLABLE FOAM-PRODUCING DEVICE ECOLAB INC (US) 2004-08-04 EP claimed
EP-1198174-B1 METHOD FOR PREVENTING THE FORMATION OF BIOLOGICAL FILMS ECOLAB INC (US) 2003-12-17 EP claimed
US-6653263-B1 Liquid lubricant between container and contact surface of moving conveyor comprising aqueous solution of fluorinated monomeric organic compound and microbiocide; food and beverage bottles; friction resistance ECOLAB INC. 2003-11-25 US claimed
US-20030139305-A1 Fluorine-containing lubricants ECOLAB INC. 2003-07-24 US claimed
WO-2003041666-A1 SELF DOSING SKIN PREPARATION INVENT RESOURCES, INC. (US) 2003-05-22 WO claimed
US-20030060484-A1 Hepatitis a viricide ECOLAB USA INC. 2003-03-27 US claimed