Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7727011 | 0.80 | KDM4E (0.43) | RAB9ASMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7983801 | 0.78 | ALDH1A1 (0.42) | RAB9ASMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL7986532 | 0.77 | TSHR (0.46) | SMN1; SMN2ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL8828519 | 0.72 | TNKS2 (0.55) | SMN1; SMN2ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL28597691 | 0.71 | ELANE (0.40) | SMN1; SMN2ALDH1A1MAPTHPGDPKM | |
| SCHEMBL5996608 | 0.68 | PARP1 (0.39) | RAB9ASMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL10624906 | 0.68 | TYMP (0.41) | ALDH1A1MAPTHPGDPKMHTT | |
| SCHEMBL7024540 | 0.68 | PARP1 (0.38) | RAB9AALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL2651667 | 0.68 | KDM4E (0.40) | ALDH1A1MAPTHPGDKMT2APKM | |
| Hydrochloric Acid SCHEMBL7723748 | 0.67 | PARP1 (0.38) | RAB9ASMN1; SMN2ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |