Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 5/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7727011 | 0.82 | KDM4E (0.43) | TSHRMAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL7986396 | 0.78 | DRD4 (0.44) | TSHRMAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL7983137 | 0.77 | RAB9A (0.41) | MAPK1KMT2AMAPTDRD3ALDH1A1 | |
| SCHEMBL8828519 | 0.76 | TNKS2 (0.55) | TSHRMEN1KMT2AMAPTTDP1 | |
| SCHEMBL5996608 | 0.70 | PARP1 (0.39) | TSHRMAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL7986389 | 0.70 | CCR3 (0.50) | KMT2AALDH1A1 | |
| SCHEMBL10624906 | 0.70 | TYMP (0.41) | MAPTALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL7723748 | 0.69 | PARP1 (0.38) | TSHRMAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL7986525 | 0.69 | CCR3 (0.56) | — | |
| SCHEMBL28597691 | 0.68 | ELANE (0.40) | MAPTALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |