Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7986162 | 0.99 | ALDH1A1 (0.43) | ALDH1A1USP2BLMKDM4EALOX15 | |
| SCHEMBL7971899 | 0.84 | DRD4 (0.52) | ALDH1A1USP2BLMKDM4ESIGMAR1 | |
| Hydrochloric Acid SCHEMBL7971892 | 0.83 | DRD4 (0.52) | ALDH1A1USP2BLMKDM4ESIGMAR1 | |
| SCHEMBL7982426 | 0.83 | LTA4H (0.47) | ALDH1A1BLMKCNH2DRD4 | |
| SCHEMBL7983992 | 0.82 | ALDH1A1 (0.42) | ALDH1A1USP2BLMKDM4ESIGMAR1 | |
| Hydrochloric Acid SCHEMBL7971795 | 0.82 | LTA4H (0.47) | ALDH1A1BLMKCNH2DRD4 | |
| SCHEMBL7971755 | 0.82 | DRD4 (0.53) | KDM4ESIGMAR1KMT2AMEN1TSHR | |
| Hydrochloric Acid SCHEMBL7983181 | 0.81 | ALDH1A1 (0.41) | ALDH1A1USP2BLMKDM4ESIGMAR1 | |
| SCHEMBL7989522 | 0.81 | CHRM4 (0.53) | DRD4 | |
| Hydrochloric Acid SCHEMBL7983770 | 0.81 | DRD4 (0.52) | KDM4ESIGMAR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |