Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7983181 | 0.99 | ALDH1A1 (0.41) | ALDH1A1KDM4EMEN1TSHRKMT2A | |
| SCHEMBL7982426 | 0.84 | LTA4H (0.47) | ALDH1A1KDM1AGRIN2BBLMKCNH2 | |
| Hydrochloric Acid SCHEMBL7971795 | 0.83 | LTA4H (0.47) | ALDH1A1KDM1AGRIN2BBLMKCNH2 | |
| SCHEMBL7989522 | 0.83 | CHRM4 (0.53) | GRIN2BCCR3 | |
| SCHEMBL7971899 | 0.82 | DRD4 (0.52) | ALDH1A1KDM4EUSP2GRIN2BBLM | |
| SCHEMBL7983161 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1TSHRKMT2A | |
| SCHEMBL7983920 | 0.82 | CHRM4 (0.48) | GRIN2BHRH3CCR3LTA4H | |
| Hydrochloric Acid SCHEMBL7972385 | 0.82 | CHRM4 (0.52) | GRIN2BCCR3 | |
| SCHEMBL7989635 | 0.82 | LTA4H (0.45) | GRIN2BCCR3SIGMAR1CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7986162 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |