⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7972990 | 0.98 | — | — | |
| SCHEMBL13763779 | 0.81 | APOBEC3A (0.40) | — | |
| SCHEMBL7983803 | 0.79 | HCAR2 (0.35) | — | |
| SCHEMBL7985758 | 0.73 | NPC1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL7972479 | 0.72 | NPC1 (0.41) | — | |
| SCHEMBL8527068 | 0.71 | L3MBTL1 (0.48) | — | |
| Hydrochloric Acid SCHEMBL7971798 | 0.71 | CHRM1 (0.40) | — | |
| SCHEMBL7986609 | 0.70 | DRD3 (0.44) | — | |
| Hydrochloric Acid SCHEMBL7983228 | 0.70 | HDAC3 (0.50) | — | |
| Hydrochloric Acid SCHEMBL7982276 | 0.69 | GAA (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10226687-A | — | — | None | — | — | JP | disclosed |
| JP-11005795-A | — | — | None | — | — | JP | disclosed |
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| JP-H115795-A | PRODUCTION OF PIPERIDINE DERIVATIVE | TAKEDA CHEM IND LTD | 1999-01-12 | — | — | JP | disclosed |
| JP-H10226687-A | IMIDAZOPYRIDINE DERIVATIVE AND ITS PRODUCTION | TAKEDA CHEM IND LTD | 1998-08-25 | — | — | JP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |