Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.45 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.39 |
| ▸ | ULK1 | O75385 | 1/20 | 0.38 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | HASPIN | Q8TF76 | 3/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7986275 | 0.99 | KDM4E (0.50) | L3MBTL1KDM4EGAAHSD17B10CAMK2D | |
| Hydrochloric Acid SCHEMBL7982276 | 0.93 | GAA (0.44) | L3MBTL1KDM4EGAAHSD17B10CAMK2D | |
| Hydrochloric Acid SCHEMBL7972033 | 0.90 | L3MBTL1 (0.41) | L3MBTL1KDM4EGAAHSD17B10CAMK2D | |
| SCHEMBL7972040 | 0.84 | SIGMAR1 (0.40) | KDM4EALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL7982606 | 0.83 | FAAH (0.39) | KDM4EALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL7983069 | 0.82 | ITGB3 (0.44) | L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7981928 | 0.82 | ALDH1A1 (0.36) | L3MBTL1KDM4EGAAHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL7982284 | 0.81 | NAMPT (0.42) | — | |
| SCHEMBL7985583 | 0.80 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL7986288 | 0.80 | DRD3 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |