Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978980 | 0.85 | ADRB3 (0.62) | ADRB3ADRB1 | |
| SCHEMBL7967611 | 0.85 | ADRB3 (0.62) | ADRB3ADRB1 | |
| SCHEMBL6906576 | 0.84 | ALOX15 (0.54) | ALOX15ADRB3ADRB1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL7108156 | 0.83 | ALOX15 (0.56) | ALOX15ADRB3ADRB1KMT2AALDH1A1 | |
| SCHEMBL7981096 | 0.81 | ADRB3 (0.45) | ADRB3MAOBTDP1 | |
| SCHEMBL7981099 | 0.81 | ADRB3 (0.45) | ADRB3MAOBTDP1 | |
| SCHEMBL7967383 | 0.80 | ALOX15 (0.51) | ALOX15ADRB3ADRB1ALDH1A1 | |
| SCHEMBL7980850 | 0.80 | ALOX15 (0.51) | ALOX15ADRB3ADRB1ALDH1A1 | |
| SCHEMBL7977145 | 0.80 | ALOX15 (0.51) | ALOX15ADRB3ADRB1ALDH1A1 | |
| SCHEMBL7980858 | 0.80 | ADRB3 (0.55) | ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172099-B1 | CARBAZOLE, DIBENZOFURAN, OR DIBENZOTHIOPHENE DERIVATIVES; DIETETICS, ANTIDIABETIC AGENTS; ANTILIPEMICS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0997458-A1 | NOVEL TRICYCLIC COMPOUNDS HAVING SATURATED RINGS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-05-03 | — | — | EP | disclosed |