Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5736687 | 0.96 | HDAC3 (0.49) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL2794680 | 0.91 | HDAC3 (0.51) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL8525848 | 0.88 | HDAC3 (0.56) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL8021840 | 0.87 | HDAC3 (0.55) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL5737640 | 0.85 | HDAC1 (0.54) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL24293612 | 0.85 | L3MBTL1 (0.48) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL18026772 | 0.84 | HDAC1 (0.47) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL5738539 | 0.84 | HDAC3 (0.53) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL13617413 | 0.84 | HDAC3 (0.53) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL6379732 | 0.84 | HDAC1 (0.53) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214833-B1 | MADE BY ACYLATION | ZAMBON GROUP S.P.A. (IT) | 2001-04-10 | — | — | US | disclosed |
| EP-0970075-A1 | PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998043972-A1 | PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1998-10-08 | — | — | WO | disclosed |