Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8495313 | 0.85 | HPGD (0.53) | KDM4EPKMFAAHHPGDGPR119 | |
| SCHEMBL21774643 | 0.84 | KDM4E (0.38) | KDM4EPKMFAAHGPR119ALDH1A1 | |
| SCHEMBL21774645 | 0.84 | KDM4E (0.38) | KDM4EPKMFAAHGPR119ALDH1A1 | |
| SCHEMBL4936669 | 0.80 | ALDH1A1 (0.33) | HPGDALDH1A1 | |
| SCHEMBL7987623 | 0.80 | HPGD (0.52) | KDM4EPKMHPGDGPR119RECQL | |
| SCHEMBL31118078 | 0.80 | FAAH (0.48) | KDM4EPKMFAAHHPGDGPR119 | |
| SCHEMBL594491 | 0.78 | KDM4E (0.51) | KDM4EPKMFAAHHPGDGPR119 | |
| SCHEMBL381974 | 0.78 | KDM4E (0.53) | KDM4EPKMFAAHHPGDGPR119 | |
| SCHEMBL792031 | 0.78 | KDM4E (0.53) | KDM4EPKMFAAHHPGDGPR119 | |
| SCHEMBL2548295 | 0.78 | GPR119 (0.52) | KDM4EPKMFAAHHPGDGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |