Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997629 | 0.85 | LMNA (0.47) | LMNAGAARAB9ANPC1ALDH1A1 | |
| SCHEMBL7997632 | 0.84 | SMN1; SMN2 (0.44) | LMNAGAAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7983870 | 0.81 | GSK3B (0.48) | LMNAGAAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7994549 | 0.80 | LMNA (0.45) | LMNAGAARAB9ANPC1ALDH1A1 | |
| SCHEMBL7997710 | 0.80 | LMNA (0.48) | LMNAGAARAB9ANPC1ALDH1A1 | |
| SCHEMBL8001444 | 0.80 | LMNA (0.51) | LMNAGAARAB9ANPC1ALDH1A1 | |
| SCHEMBL7963994 | 0.79 | LMNA (0.50) | LMNAGAARAB9ANPC1ALDH1A1 | |
| SCHEMBL7994274 | 0.79 | LMNA (0.46) | LMNAGAAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7995873 | 0.79 | LMNA (0.45) | LMNAGAARAB9ANPC1ALDH1A1 | |
| SCHEMBL7994118 | 0.78 | ALDH1A1 (0.46) | LMNAGAAALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |