Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997882 | 0.86 | LMNA (0.43) | SMN1; SMN2LMNAMAPTL3MBTL1NPSR1 | |
| SCHEMBL7997644 | 0.85 | LMNA (0.44) | SMN1; SMN2LMNAMAPTL3MBTL1NPSR1 | |
| SCHEMBL7997738 | 0.85 | LMNA (0.41) | SMN1; SMN2LMNAMAPTL3MBTL1NPSR1 | |
| SCHEMBL7997378 | 0.85 | LMNA (0.41) | SMN1; SMN2LMNAMAPTL3MBTL1NPSR1 | |
| SCHEMBL7983528 | 0.84 | LMNA (0.44) | SMN1; SMN2LMNAMAPTL3MBTL1NPSR1 | |
| SCHEMBL7983861 | 0.84 | NPSR1 (0.51) | SMN1; SMN2LMNAMAPTL3MBTL1NPSR1 | |
| SCHEMBL7997629 | 0.84 | LMNA (0.47) | SMN1; SMN2LMNAMAPTL3MBTL1NPSR1 | |
| SCHEMBL7995873 | 0.83 | LMNA (0.45) | SMN1; SMN2LMNAMAPTL3MBTL1NPSR1 | |
| SCHEMBL7995815 | 0.83 | CYP11B1 (0.45) | SMN1; SMN2LMNAMAPTL3MBTL1NPSR1 | |
| SCHEMBL7983888 | 0.82 | LMNA (0.43) | SMN1; SMN2LMNAMAPTL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |