Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991085 | 0.89 | LMNA (0.54) | LMNAKMT2AMAPTMEN1NR1I2 | |
| SCHEMBL7974560 | 0.87 | HCRTR1 (0.53) | LMNAKMT2AMAPTMEN1L3MBTL1 | |
| SCHEMBL7973346 | 0.82 | CTSD (0.50) | LMNAKMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL1083152 | 0.81 | LMNA (0.57) | LMNAKMT2AMAPTMEN1NR1I2 | |
| SCHEMBL1082961 | 0.81 | LMNA (0.57) | LMNAKMT2AMAPTMEN1NR1I2 | |
| SCHEMBL7984830 | 0.80 | HCRTR1 (0.49) | LMNAKMT2AMAPTMEN1L3MBTL1 | |
| SCHEMBL7987852 | 0.78 | IRAK4 (0.54) | LMNAALDH1A1TDP1KDM4ERXFP1 | |
| SCHEMBL12419023 | 0.78 | LMNA (0.55) | LMNAKMT2AMAPTMEN1NR1I2 | |
| SCHEMBL9898531 | 0.78 | LMNA (0.66) | LMNAKMT2AMAPTMEN1NR1I2 | |
| SCHEMBL8154526 | 0.77 | LMNA (0.74) | LMNAKMT2AMAPTMEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |