Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974560 | 0.90 | HCRTR1 (0.53) | HCRTR1MAPTGAAMAPK1HSD17B10 | |
| SCHEMBL7987106 | 0.87 | CTSD (0.46) | MAPTMAPK1NPSR1GLAHTT | |
| SCHEMBL7983681 | 0.84 | HCRTR1 (0.53) | HCRTR1MAPTGAAMAPK1HSD17B10 | |
| SCHEMBL7987117 | 0.83 | IRAK4 (0.50) | HCRTR1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7983548 | 0.80 | LMNA (0.54) | MAPTTSHRL3MBTL1NPSR1MEN1 | |
| SCHEMBL7973353 | 0.79 | SLC6A2 (0.36) | MEN1KMT2A | |
| SCHEMBL7990893 | 0.79 | USP2 (0.38) | GAATSHRKMT2AHTTKDM4E | |
| SCHEMBL7973452 | 0.78 | NPC1 (0.39) | MAPTNPSR1KMT2AHTTALDH1A1 | |
| SCHEMBL7991901 | 0.78 | USP2 (0.49) | MAPTGAATSHRGLAHTT | |
| SCHEMBL7990928 | 0.78 | HPGD (0.44) | ALDH1A1LMNAHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |