Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 4/20 | 0.64 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | MERTK | Q12866 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4477143 | 0.82 | VCAM1 (0.70) | VCAM1KAT2BMAPTMAPK1TDP1 | |
| SCHEMBL103929 | 0.81 | VCAM1 (0.64) | VCAM1KAT2BMAPTMAPK1RAB9A | |
| SCHEMBL31326843 | 0.81 | VCAM1 (0.64) | VCAM1KAT2BMAPTMAPK1RAB9A | |
| SCHEMBL8143514 | 0.79 | VCAM1 (0.66) | VCAM1KAT2BMAPTMAPK1TDP1 | |
| SCHEMBL11592812 | 0.79 | VCAM1 (0.66) | VCAM1KAT2BMAPTMAPK1TDP1 | |
| SCHEMBL10876367 | 0.78 | VCAM1 (0.64) | VCAM1KAT2BMAPTMAPK1TDP1 | |
| SCHEMBL6516751 | 0.78 | VCAM1 (0.64) | VCAM1KAT2BMAPTMAPK1TDP1 | |
| SCHEMBL203082 | 0.78 | VCAM1 (0.64) | VCAM1KAT2BMAPTMAPK1TDP1 | |
| SCHEMBL323126 | 0.78 | VCAM1 (0.64) | VCAM1KAT2BMAPTMAPK1TDP1 | |
| SCHEMBL6463 | 0.78 | VCAM1 (1.00) | VCAM1KAT2BMAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547713-B2 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | GU LIANQUAN | 2009-06-16 | — | — | US | claimed |
| US-20060111405-A1 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | GU LIANQUAN | 2006-05-25 | — | — | US | claimed |
| US-7547713-B2 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | GU LIANQUAN | 2009-06-16 | — | — | US | disclosed |
| US-20060111405-A1 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | GU LIANQUAN | 2006-05-25 | — | — | US | disclosed |
| US-6121239-A | SPECIFIED TRI- AND TETRA-PEPTIDES | SERBIO (FR) | 2000-09-19 | — | — | US | disclosed |
| EP-0476107-B1 | PROCESS FOR IDENTIFYING CANDIDA ALBICANS BY MEANS OF CHROMOGENIC SUBSTANCES | STAGO DIAGNOSTICA (FR) | 1996-06-19 | — | — | EP | disclosed |
| US-5449612-A | Process for identifying candida by means of chromogenic substances | SERBIO (FR) | 1995-09-12 | — | — | US | disclosed |
| EP-0472670-B1 | SYMMETRICAL BIPEPTIDES INCLUDING A POLYALKYLENE-GYLCOL GROUP, METHOD OF PREPARATION AND USE IN PROTEASE DETERMINATION | SERBIO (FR) | 1995-03-29 | — | — | EP | disclosed |
| EP-0472671-B1 | PEPTIDE SUBSTRATES FOR Xa FACTOR IDENTIFICATION | SERBIO (FR) | 1995-03-15 | — | — | EP | disclosed |
| EP-0469102-B1 | NOVEL PEPTIDE SUBSTRATES, METHOD OF PREPARATION AND USE IN C PROTEIN DETERMINATION | SERBIO (FR) | 1995-03-01 | — | — | EP | disclosed |
| US-5362851-A | Tripeptides | SERBIO (FR) | 1994-11-08 | — | — | US | disclosed |
| EP-0476107-A1 | PROCESS FOR IDENTIFYING CANDIDA BY MEANS OF CHROMOGENIC SUBSTANCES. | SERBIO (FR) | 1992-03-25 | — | — | EP | disclosed |
| EP-0472671-A1 | PEPTIDE SUBSTRATES FOR Xa FACTOR IDENTIFICATION. | SERBIO (FR) | 1992-03-04 | — | — | EP | disclosed |
| EP-0472670-A1 | SYMMETRICAL BIPEPTIDES INCLUDING A POLYALKYLENE-GYLCOL GROUP, METHOD OF PREPARATION AND USE IN PROTEASE DETERMINATION. | SERBIO (FR) | 1992-03-04 | — | — | EP | disclosed |
| EP-0469102-A1 | NOVEL PEPTIDE SUBSTRATES, METHOD OF PREPARATION AND USE IN C PROTEIN DETERMINATION. | SERBIO (FR) | 1992-02-05 | — | — | EP | disclosed |
| WO-1991014787-A1 | PROCESS FOR IDENTIFYING CANDIDA BY MEANS OF CHROMOGENIC SUBSTANCES | SERBIO (FR) | 1991-10-03 | — | — | WO | disclosed |
| WO-1991012268-A1 | NOVEL PEPTIDE SUBSTRATES, METHOD OF PREPARATION AND USE IN C PROTEIN DETERMINATION | SERBIO (FR) | 1991-08-22 | — | — | WO | disclosed |
| WO-1991012338-A1 | PEPTIDE SUBSTRATES FOR Xa FACTOR IDENTIFICATION | SERBIO (FR) | 1991-08-22 | — | — | WO | disclosed |
| WO-1991012263-A1 | SYMMETRICAL BIPEPTIDES INCLUDING A POLYALKYLENE-GYLCOL GROUP, METHOD OF PREPARATION AND USE IN PROTEASE DETERMINATION | SERBIO (FR) | 1991-08-22 | — | — | WO | disclosed |
| EP-0280610-A1 | Dipeptides, preparation process and use in dosing proteases | SERBIO (FR) | 1988-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111405-A1 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | PTGS2, PTGES2, PTGES | VCAM1 4140/4885KAT2B 4422/4885MAPT 3965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.