Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 4/20 | 0.64 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | MERTK | Q12866 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6518931 | 0.98 | VCAM1 (0.62) | VCAM1KAT2BMAPTMAPK1TDP1 | |
| Zinc Ion SCHEMBL6513181 | 0.98 | VCAM1 (0.62) | VCAM1KAT2BMAPTMAPK1TDP1 | |
| SCHEMBL6513178 | 0.98 | VCAM1 (0.62) | VCAM1KAT2BMAPTMAPK1TDP1 | |
| SCHEMBL6518933 | 0.98 | VCAM1 (0.62) | VCAM1KAT2BMAPTMAPK1TDP1 | |
| SCHEMBL6518935 | 0.98 | VCAM1 (0.62) | VCAM1KAT2BMAPTMAPK1TDP1 | |
| SCHEMBL4477143 | 0.82 | VCAM1 (0.70) | VCAM1KAT2BMAPTMAPK1TDP1 | |
| SCHEMBL8143514 | 0.79 | VCAM1 (0.66) | VCAM1KAT2BMAPTMAPK1TDP1 | |
| SCHEMBL323126 | 0.78 | VCAM1 (0.64) | VCAM1KAT2BMAPTMAPK1TDP1 | |
| SCHEMBL4056837 | 0.78 | VCAM1 (0.64) | VCAM1KAT2BMAPTMAPK1TDP1 | |
| SCHEMBL7983550 | 0.78 | VCAM1 (0.64) | VCAM1KAT2BMAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11046644-B2 | Sulfur derivatives as chemokine receptor modulators | ALLERGAN, INC. (US) | 2021-06-29 | — | — | US | disclosed |
| US-11046644-B2 | Sulfur derivatives as chemokine receptor modulators | ALLERGAN, INC. (US) | 2021-06-29 | — | — | US | disclosed |
| EP-3292893-B1 | GOLF BALL | SUMITOMO RUBBER IND (JP) | 2021-06-09 | — | — | EP | disclosed |
| EP-2656882-B1 | Golf ball | SUMITOMO RUBBER IND (JP) | 2021-06-09 | — | — | EP | disclosed |
| EP-3156441-B1 | GOLF BALL | SUMITOMO RUBBER IND (JP) | 2020-11-25 | — | — | EP | disclosed |
| EP-3329971-B1 | GOLF BALL | SUMITOMO RUBBER IND (JP) | 2020-11-18 | — | — | EP | disclosed |
| EP-2666521-B1 | Golf ball | SUMITOMO RUBBER IND (JP) | 2020-09-02 | — | — | EP | disclosed |
| US-20200109110-A1 | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN INC (US) | 2020-04-09 | — | — | US | disclosed |
| EP-2669326-B1 | Golf ball | SUMITOMO RUBBER IND (JP) | 2019-06-12 | — | — | EP | disclosed |
| US-10286258-B2 | Golf ball | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2019-05-14 | — | — | US | disclosed |
| US-20120157487-A1 | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20120157487-A1 | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20120142453-A1 | GOLF BALL | SRI SPORTS LIMITED (JP) | 2012-06-07 | — | — | US | disclosed |
| US-6919393-B2 | Solid golf ball | SRI SPORTS LIMITED (JP) | 2005-07-19 | — | — | US | disclosed |
| US-20030144425-A1 | Solid golf ball | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2003-07-31 | — | — | US | disclosed |
| US-20030144427-A1 | Solid golf ball | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2003-07-31 | — | — | US | disclosed |
| EP-0034759-B1 | CHROMOGEN CEPHALOSPORINS AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-02 | — | — | EP | disclosed |
| US-4535156-A | DECTECTION OF BETA-LACTAMINASE AND BETA-LACTAMASE INHIBITORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-08-13 | — | — | US | disclosed |
| EP-0034759-A2 | Chromogen cephalosporins and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-02 | — | — | EP | disclosed |
| US-4066641-A | METHOD FOR CYCLIZATION TO GIVE CEPHEM RING | HAMASHIMA YOSHIO | 1978-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157487-A1 | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | CX3CR1, CXCR2, CCR2 | VCAM1 255/4885KAT2B 4435/4885MAPT 4253/4885 |
| US-20200109110-A1 | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | CX3CR1, CXCR2, CCR2 | VCAM1 255/4885KAT2B 4435/4885MAPT 4253/4885 |
| US-11046644-B2 | Sulfur derivatives as chemokine receptor modulators | CX3CR1, CXCR2, CCR2 | VCAM1 255/4885KAT2B 4435/4885MAPT 4253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.