Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 9/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7981574 | 0.99 | SMYD2 (0.45) | SMYD2CYP2D6SMAD3ALDH1A1KDM4E | |
| SCHEMBL7987161 | 0.97 | SMYD2 (0.42) | SMYD2CYP2D6SMAD3ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7971940 | 0.96 | SMYD2 (0.41) | SMYD2CYP2D6SMAD3ALDH1A1KDM4E | |
| SCHEMBL7985583 | 0.94 | ALDH1A1 (0.43) | SMYD2ALDH1A1 | |
| SCHEMBL7984706 | 0.93 | DRD3 (0.42) | CYP2D6ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7983892 | 0.93 | ALDH1A1 (0.42) | SMYD2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7982703 | 0.92 | DRD3 (0.42) | CYP2D6ALDH1A1KDM4E | |
| SCHEMBL7986609 | 0.90 | DRD3 (0.44) | CYP2D6ALDH1A1 | |
| SCHEMBL7972040 | 0.90 | SIGMAR1 (0.40) | ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7981722 | 0.90 | DRD3 (0.44) | CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |