Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.39 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.39 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17826925 | 0.88 | AAK1 (0.46) | TRPV1MTNR1AMTNR1BSCN9AAAK1 | |
| SCHEMBL23126845 | 0.85 | MAPT (0.50) | TRPV1MTNR1AMTNR1BTP53MAPT | |
| SCHEMBL29378369 | 0.85 | MAPT (0.50) | TRPV1MTNR1AMTNR1BTP53MAPT | |
| SCHEMBL28552129 | 0.85 | MAPT (0.50) | TRPV1MTNR1AMTNR1BTP53MAPT | |
| SCHEMBL7995640 | 0.83 | ALDH1A1 (0.50) | TRPV1MTNR1AMTNR1BSCN9ASYK | |
| Trimethylammonium SCHEMBL9095683 | 0.82 | MAPT (0.47) | TRPV1MTNR1AMTNR1BTP53MAPT | |
| SCHEMBL7998062 | 0.81 | TRPV1 (0.46) | TRPV1MTNR1AMTNR1BMAPTTACR1 | |
| SCHEMBL17826908 | 0.81 | MTNR1A (0.54) | TRPV1MTNR1AMTNR1BAAK1 | |
| SCHEMBL1249782 | 0.80 | MTNR1A (0.56) | TRPV1MTNR1AMTNR1BSCN9ASERPINE1 | |
| SCHEMBL2534000 | 0.77 | TYR (0.62) | TRPV1MTNR1AMTNR1BNQO2SPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040183-A1 | 1-AMINOALKYL-1H-INDOLES FOR TREATING GLAUCOMA | ALCON UNIVERSAL LTD. (CH) | 2001-06-07 | — | — | WO | disclosed |