Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | NMBR | P28336 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BMP1 | P13497 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983683 | 0.81 | TRPV1 (0.51) | TRPV1MTNR1AMTNR1BMAPTTACR1 | |
| SCHEMBL9765283 | 0.79 | LMNA (0.45) | HTTLMNASMN1; SMN2 | |
| SCHEMBL7995640 | 0.78 | ALDH1A1 (0.50) | TRPV1MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL9765305 | 0.75 | LMNA (0.51) | MEN1KMT2AHTTLMNASMN1; SMN2 | |
| SCHEMBL13073758 | 0.74 | LMNA (0.55) | MEN1KMT2AHTTLMNASMN1; SMN2 | |
| SCHEMBL13073762 | 0.74 | LMNA (0.55) | MEN1KMT2AHTTLMNASMN1; SMN2 | |
| SCHEMBL9092208 | 0.73 | NMBR (0.48) | NMBRBMP1GAAMAPTHTT | |
| SCHEMBL4431806 | 0.72 | LMNA (0.56) | HTTLMNASMN1; SMN2 | |
| SCHEMBL4430839 | 0.72 | LMNA (0.56) | HTTLMNASMN1; SMN2 | |
| SCHEMBL4430842 | 0.72 | LMNA (0.56) | HTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040183-A1 | 1-AMINOALKYL-1H-INDOLES FOR TREATING GLAUCOMA | ALCON UNIVERSAL LTD. (CH) | 2001-06-07 | — | — | WO | disclosed |