SCHEMBL7983789

SCHEMBL7983789

NCc1nc(OC(=O)O)cs1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 9/20 0.36
GABRA5 P31644 1/20 0.33
GABRB2 P47870 1/20 0.33
HSD17B10 Q99714 1/20 0.33
LOXL3 P58215 1/20 0.32
CDK5 Q00535 1/20 0.31
CDK5R1 Q15078 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1417466 0.76 GABRA5 (0.47) GABRA5GABRB2HSD17B10MEN1
SCHEMBL252583 0.73 HDAC3 (0.38)
SCHEMBL3597949 0.72 MMP1 (0.53) LOXL2
SCHEMBL7984989 0.71 KDM4E (0.50) MEN1
SCHEMBL4672078 0.70 PPARD (0.50) CDK5CDK5R1
SCHEMBL2642506 0.70 AOC3 (0.36) LOXL2LOXL3MEN1
Hydrochloric Acid SCHEMBL23120712 0.70 MMP1 (0.51) LOXL2
SCHEMBL26998918 0.69 HSD17B10 (0.62) LOXL2GABRA5GABRB2HSD17B10
SCHEMBL4675305 0.69 MAPT (0.58)
SCHEMBL4671833 0.69 BCHE (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001027095-A1 METHOD FOR PRODUCING 2-(N-BOC-AMINOMETHYL)-THIAZOL-4-CARBOXYLIC ACID BASF AKTIENGESELLSCHAFT (DE) 2001-04-19 WO claimed
WO-2001027095-A1 METHOD FOR PRODUCING 2-(N-BOC-AMINOMETHYL)-THIAZOL-4-CARBOXYLIC ACID BASF AKTIENGESELLSCHAFT (DE) 2001-04-19 WO disclosed
WO-2001027095-A1 METHOD FOR PRODUCING 2-(N-BOC-AMINOMETHYL)-THIAZOL-4-CARBOXYLIC ACID BASF AKTIENGESELLSCHAFT (DE) 2001-04-19 WO disclosed