Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
| ▸ | GRK2 | P25098 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2711084 | 0.79 | NPC1 (0.58) | KDM4ENPC1HPGDMAPTMAPK1 | |
| SCHEMBL7984987 | 0.79 | KDM4E (0.53) | KDM4ENPC1HPGDMAPTMAPK1 | |
| SCHEMBL2227256 | 0.78 | MAPT (0.67) | KDM4ENPC1HPGDMAPTMAPK1 | |
| SCHEMBL7260803 | 0.74 | RAB9A (0.67) | KDM4ENPC1HPGDMAPTMAPK1 | |
| SCHEMBL7983789 | 0.71 | LOXL2 (0.36) | MEN1 | |
| SCHEMBL13118304 | 0.70 | NPC1 (0.60) | KDM4ENPC1HPGDLMNAROCK2 | |
| SCHEMBL4672078 | 0.69 | PPARD (0.50) | KDM4ENPC1MAPTPOLBRAB9A | |
| SCHEMBL1491324 | 0.69 | MGLL (0.46) | NPC1LMNAENPP2HDAC1HDAC6 | |
| SCHEMBL4152631 | 0.69 | MAPK14 (0.60) | KDM4ENPC1HPGDMAPTLMNA | |
| SCHEMBL7447830 | 0.68 | ROCK2 (0.65) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001027095-A1 | METHOD FOR PRODUCING 2-(N-BOC-AMINOMETHYL)-THIAZOL-4-CARBOXYLIC ACID | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-19 | — | — | WO | disclosed |