Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14176047 | 0.84 | KDM4E (0.56) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL6997715 | 0.84 | KDM4E (0.56) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL5016641 | 0.84 | SMN1; SMN2 (0.64) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL30912172 | 0.84 | SMN1; SMN2 (0.64) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL18582934 | 0.84 | SMN1; SMN2 (0.64) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL5058433 | 0.84 | SMN1; SMN2 (0.64) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL7983585 | 0.83 | CA1 (0.42) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL2763754 | 0.83 | ALDH1A1 (0.53) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL30680392 | 0.83 | ALDH1A1 (0.53) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL29682646 | 0.83 | ALDH1A1 (0.53) | NPC1RAB9AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061514-B | Organometallic complex and light-emitting component, light-emitting device and electronic device | 株式会社半导体能源研究所 | 2018-05-08 | — | — | CN | disclosed |
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| EP-0586608-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |