SCHEMBL5058433

SCHEMBL5058433

c1ccc2c(c1)Cc1cc3c(cc1-2)Cc1ccccc1-3

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.64
NPC1 O15118 3/20 0.64
MAPT P10636 3/20 0.64
RAB9A P51151 3/20 0.64
ALDH1A1 P00352 2/20 0.64
KDM4E B2RXH2 2/20 0.64
HPGD P15428 2/20 0.64
LMNA P02545 1/20 0.64
MAOA P21397 2/20 0.56
SRD5A2 P31213 1/20 0.55
CYP1A2 P05177 4/20 0.52
CYP3A4 P08684 4/20 0.52
HTR2C P28335 2/20 0.48
HTR2B P41595 2/20 0.48
ADRA2A P08913 1/20 0.48
SLC6A2 P23975 1/20 0.48
SLC6A4 P31645 1/20 0.48
PGR P06401 2/20 0.47
BCHE P06276 1/20 0.46
CES1 P23141 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18582934 1.00 SMN1; SMN2 (0.64) SMN1; SMN2NPC1MAPTRAB9AALDH1A1
SCHEMBL30912172 1.00 SMN1; SMN2 (0.64) SMN1; SMN2NPC1MAPTRAB9AALDH1A1
SCHEMBL5016641 1.00 SMN1; SMN2 (0.64) SMN1; SMN2NPC1MAPTRAB9AALDH1A1
SCHEMBL29924230 0.92 SMN1; SMN2 (0.61) SMN1; SMN2NPC1MAPTRAB9AALDH1A1
SCHEMBL3280539 0.92 SMN1; SMN2 (0.61) SMN1; SMN2NPC1MAPTRAB9AALDH1A1
SCHEMBL5357317 0.91 RAB9A (0.55) SMN1; SMN2NPC1MAPTRAB9AALDH1A1
SCHEMBL2720506 0.88 ALDH1A1 (0.70) SMN1; SMN2NPC1MAPTRAB9AALDH1A1
Fluorene SCHEMBL8180 0.88 MAOA (0.68) SMN1; SMN2NPC1MAPTRAB9AALDH1A1
Fluorene SCHEMBL31388525 0.88 MAOA (0.68) SMN1; SMN2NPC1MAPTRAB9AALDH1A1
Fluorene SCHEMBL29478468 0.88 MAOA (0.68) SMN1; SMN2NPC1MAPTRAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7271406-B2 Electron transport agents for organic electronic devices 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-09-18 US claimed
US-6835296-B2 Electrochemical polymerization; polyfluorenone; light emitting diodes IM&T RESEARCH, INC. 2004-12-28 US claimed
US-6767446-B2 ELECTROLYTIC POLYMERIZATION OF AROMATIC HYDROCARBONS SUCH AS FLUORENE IN THE PRESENCE OF AN ESTER; OXIDIZING RESULTING POLYMER TO PRODUCE A CYCLOPENTANONE-CONTAINING POLYMER SUCH AS POLY(9-FLUORENONE); LIGHT EMITTING DIODES IM&T RESEARCH, INC. 2004-07-27 US claimed
US-20030081432-A1 Electrolytic polymerization of aromatic hydrocarbons such as fluorene in the presence of an ester; oxidizing resulting polymer to produce a cyclopentanone-containing polymer such as poly(9-fluorenone); light emitting diodes IM&T RESEARCH, INC. 2003-05-01 US claimed
US-20030066757-A1 Method for preparing polymers containing cyclopentanone structures IM&T RESEARCH, INC. 2003-04-10 US claimed
US-12384964-B2 Conjugated polymers and methods of use BioLegend, Inc. (US) 2025-08-12 US disclosed
US-20250066527-A1 CROSS-LINKABLE ION EXCHANGE POLYMERS, MEMBRANES AND IONOMERS UCHICAGO ARGONNE, LLC 2025-02-27 US disclosed
US-12024480-B2 Polynitroso compound, its preparation and electrochemical use CITY UNIVERSITY OF HONG KONG (HK) 2024-07-02 US disclosed
US-20240182403-A1 POLYNITROSO COMPOUND, ITS PREPARATION AND ELECTROCHEMICAL USE CITY UNIVERSITY OF HONG KONG (HK) 2024-06-06 US disclosed
US-11912816-B2 Polymer and light-emitting device INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2024-02-27 US disclosed
US-20230322694-A1 COMPOUND SUMITOMO CHEMICAL CO., LTD (JP) 2023-10-12 US disclosed
US-20230212335-A1 Polymeric Compound, Electroluminescent Device Material, Electroluminescent Device, and Electronic Device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-06 US disclosed
US-7087681-B2 Electrochemistry polymerization; blend of aromatic resin and cyclopentanone ; oxidation to polyfluorenes IM&T RESEARCH, INC. (US) 2006-08-08 US disclosed
US-20050045492-A1 Method for preparing polymers containing cyclopentanone structures IM&T RESEARCH, INC. 2005-03-03 US disclosed
US-6835296-B2 Electrochemical polymerization; polyfluorenone; light emitting diodes IM&T RESEARCH, INC. 2004-12-28 US disclosed
US-20040206633-A1 oxidation of aromatic hydrocarbons into cyclopentanone compound; oxidation of fluorene into polyfluorenone IM&T RESEARCH, INC. 2004-10-21 US disclosed
US-20040210033-A1 Electrochemistry polymerization; blend of aromatic resin and cyclopentanone ; oxidation to polyfluorenes IM&T RESEARCH, INC. 2004-10-21 US disclosed
US-6767446-B2 ELECTROLYTIC POLYMERIZATION OF AROMATIC HYDROCARBONS SUCH AS FLUORENE IN THE PRESENCE OF AN ESTER; OXIDIZING RESULTING POLYMER TO PRODUCE A CYCLOPENTANONE-CONTAINING POLYMER SUCH AS POLY(9-FLUORENONE); LIGHT EMITTING DIODES IM&T RESEARCH, INC. 2004-07-27 US disclosed
US-20030081432-A1 Electrolytic polymerization of aromatic hydrocarbons such as fluorene in the presence of an ester; oxidizing resulting polymer to produce a cyclopentanone-containing polymer such as poly(9-fluorenone); light emitting diodes IM&T RESEARCH, INC. 2003-05-01 US disclosed
US-20030066757-A1 Method for preparing polymers containing cyclopentanone structures IM&T RESEARCH, INC. 2003-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12024480-B2 Polynitroso compound, its preparation and electrochemical use PNPO, NOXO1, MT-ND6 SMN1; SMN2 1326/4885NPC1 3298/4885MAPT 3780/4885
US-20240182403-A1 POLYNITROSO COMPOUND, ITS PREPARATION AND ELECTROCHEMICAL USE PNPO, NOXO1, MT-ND6 SMN1; SMN2 1326/4885NPC1 3298/4885MAPT 3780/4885
US-20230322694-A1 COMPOUND RAD51, NR0B1, XRN2 SMN1; SMN2 2344/4885NPC1 3269/4885MAPT 2841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.