Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994841 | 0.93 | LMNA (0.40) | NTRK1POLBHPGDHTTSTING1 | |
| SCHEMBL7983679 | 0.88 | HPGD (0.40) | POLBHPGDSTING1LMNASMN1; SMN2 | |
| SCHEMBL7984211 | 0.84 | STING1 (0.43) | STING1L3MBTL1 | |
| SCHEMBL7997825 | 0.80 | STING1 (0.47) | STING1L3MBTL1 | |
| SCHEMBL7984304 | 0.80 | STING1 (0.49) | STING1RAB9ANPC1L3MBTL1 | |
| SCHEMBL7983874 | 0.79 | STING1 (0.43) | HTTSTING1LMNASMN1; SMN2RAB9A | |
| SCHEMBL7995372 | 0.79 | STING1 (0.42) | STING1L3MBTL1KMT2A | |
| SCHEMBL7983932 | 0.79 | STING1 (0.42) | POLBSTING1L3MBTL1KMT2A | |
| SCHEMBL7998407 | 0.78 | STING1 (0.41) | STING1L3MBTL1 | |
| SCHEMBL7995743 | 0.75 | STING1 (0.41) | STING1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |