Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | CRACR2A | Q9BSW2 | 3/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26719552 | 0.83 | ALDH1A1 (0.40) | NTRK1KMT2APKMKDM4ECRACR2A | |
| SCHEMBL8615297 | 0.80 | KDM4E (0.41) | NTRK1KMT2APKMPOLBKDM4E | |
| Ammonia Solution, Strong SCHEMBL27582988 | 0.80 | KDM4E (0.50) | NTRK1KMT2APKMKDM4ECRACR2A | |
| Methane SCHEMBL28112164 | 0.80 | KDM4E (0.50) | NTRK1KMT2APKMKDM4ECRACR2A | |
| SCHEMBL1417795 | 0.78 | KDM4E (0.52) | NTRK1KMT2APKMKDM4ECRACR2A | |
| Ethane SCHEMBL27993176 | 0.77 | KDM4E (0.39) | NTRK1KMT2APKMKDM4ECRACR2A | |
| SCHEMBL20298538 | 0.77 | KDM4E (0.37) | NTRK1KMT2APKMKDM4ECRACR2A | |
| SCHEMBL3110519 | 0.77 | KDM4E (0.37) | NTRK1KMT2APKMKDM4ECRACR2A | |
| SCHEMBL31391808 | 0.74 | KDM4E (0.62) | KMT2APKMKDM4ECRACR2ABAZ2B | |
| SCHEMBL10821292 | 0.72 | KDM4E (0.34) | NTRK1KMT2APKMKDM4ECRACR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130281500-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-24 | — | — | US | disclosed |
| US-20130281496-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-24 | — | — | US | disclosed |
| US-20130281292-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-24 | — | — | US | disclosed |
| US-8377923-B2 | Triazole derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2013-02-19 | — | — | US | disclosed |
| US-8377923-B2 | Triazole derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2013-02-19 | — | — | US | disclosed |
| US-20110105460-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-05-05 | — | — | US | disclosed |
| US-20110105460-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-05-05 | — | — | US | disclosed |
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281496-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | NTRK1 3880/4885KMT2A 1733/4885PKM 2914/4885 |
| US-20130281500-A1 | Synergistic Fungicidal Active Substance Combinations | CAT, CYP1A2, GABBR1 | NTRK1 4037/4885KMT2A 1600/4885PKM 2577/4885 |
| US-20110105460-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | HSD11B1, HSD11B2, HSD3B1 | NTRK1 2692/4885KMT2A 2930/4885PKM 3142/4885 |
| US-20130281292-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | NTRK1 3880/4885KMT2A 1733/4885PKM 2914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.