Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 8/20 | 1.00 |
| ▸ | PRKACA | P17612 | 3/20 | 0.54 |
| ▸ | PRKACG | P22612 | 3/20 | 0.54 |
| ▸ | PRKACB | P22694 | 3/20 | 0.54 |
| ▸ | NOX4 | Q9NPH5 | 5/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984187 | 0.79 | SRC (1.00) | SRCPRKACAPRKACGPRKACBKDM4E | |
| SCHEMBL9367302 | 0.78 | SRC (1.00) | SRCPRKACAPRKACGPRKACBNOX4 | |
| SCHEMBL7980611 | 0.75 | SRC (0.60) | SRCKDM4ECYP2C19L3MBTL1PGR | |
| SCHEMBL7983612 | 0.74 | SRC (0.70) | SRCPRKACAPRKACGPRKACBNOX4 | |
| SCHEMBL11267711 | 0.73 | ALDH1A1 (0.58) | SRCKDM4ECYP1A2L3MBTL1ALDH1A1 | |
| SCHEMBL7983999 | 0.71 | SRC (1.00) | SRCPRKACAPRKACGPRKACBNOX4 | |
| SCHEMBL7981059 | 0.70 | SRC (1.00) | SRCPRKACAPRKACGPRKACBNOX4 | |
| SCHEMBL7983614 | 0.70 | SRC (0.52) | SRCPRKACAPRKACGPRKACBNOX4 | |
| SCHEMBL14549005 | 0.69 | SRC (0.53) | SRCGPR35KDM4ECYP1A2CYP3A4 | |
| SCHEMBL7981707 | 0.69 | SRC (1.00) | SRCPRKACAPRKACGPRKACBNOX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |