Sugi Predict

Sugi Predict / Compounds / SCHEMBL7984100

SCHEMBL7984100

SCHEMBL7984100

O=S(=O)(c1ccccc1)n1c2cc(O)c(O)cc2c2ccc(O)c(O)c21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ SRC P12931 20/20 1.00
▸ PRKACA P17612 9/20 0.66
▸ PRKACG P22612 9/20 0.66
▸ PRKACB P22694 9/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7969684 0.86 SRC (1.00) SRCPRKACAPRKACGPRKACB
SCHEMBL7984148 0.83 SRC (1.00) SRCPRKACAPRKACGPRKACB
SCHEMBL7980678 0.80 SRC (1.00) SRCPRKACAPRKACGPRKACB
SCHEMBL7987642 0.79 SRC (0.65) SRCPRKACAPRKACGPRKACB
SCHEMBL7988542 0.75 SRC (1.00) SRCPRKACAPRKACGPRKACB
SCHEMBL7987325 0.73 SRC (1.00) SRCPRKACAPRKACGPRKACB
SCHEMBL7984723 0.71 SRC (1.00) SRCPRKACAPRKACGPRKACB
SCHEMBL7987332 0.71 SRC (0.72) SRCPRKACAPRKACGPRKACB
SCHEMBL7981658 0.70 SRC (1.00) SRCPRKACAPRKACGPRKACB
SCHEMBL7987588 0.68 SRC (1.00) SRCPRKACAPRKACGPRKACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6194439-B1 ANTICANCER AGENT PFIZER INC. 2001-02-27 — — US disclosed
EP-0586608-A1 TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS PFIZER INC. (US) 1994-03-16 — — EP disclosed
WO-1992021660-A1 TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS PFIZER, INC. (US) 1992-12-10 — — WO disclosed