Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 18/20 | 0.72 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.72 |
| ▸ | PRKACA | P17612 | 7/20 | 0.52 |
| ▸ | PRKACG | P22612 | 7/20 | 0.52 |
| ▸ | PRKACB | P22694 | 7/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981611 | 0.87 | NOX4 (0.77) | SRCNOX4PRKACAPRKACGPRKACB | |
| SCHEMBL7987325 | 0.84 | SRC (1.00) | SRCNOX4PRKACAPRKACGPRKACB | |
| SCHEMBL7981060 | 0.84 | NOX4 (1.00) | SRCNOX4PRKACAPRKACGPRKACB | |
| SCHEMBL7981658 | 0.78 | SRC (1.00) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7983976 | 0.73 | NOX4 (0.49) | SRCNOX4PTGDR2 | |
| SCHEMBL7984100 | 0.71 | SRC (1.00) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7981604 | 0.71 | SRC (1.00) | SRCNOX4PRKACAPRKACGPRKACB | |
| SCHEMBL7983706 | 0.69 | SRC (1.00) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7981378 | 0.69 | SRC (1.00) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7981609 | 0.68 | SRC (1.00) | SRCPRKACAPRKACGPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |