SCHEMBL7984128

SCHEMBL7984128

C[C@@](Cc1ccc(O)cc1)(NS(=O)(=O)c1ccccc1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 1/20 0.48
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
GHSR Q92847 2/20 0.43
BCAT1 P54687 1/20 0.42
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 2/20 0.42
MAPT P10636 2/20 0.42
LMNA P02545 1/20 0.42
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
CYP3A4 P08684 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
MAPK1 P28482 1/20 0.42
THPO P40225 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7984126 1.00 BLM (0.48) BLMMEN1KMT2AGHSRBCAT1
SCHEMBL6255022 0.89 GHSR (0.46) BLMMEN1KMT2AGHSRALDH1A1
SCHEMBL6255018 0.89 GHSR (0.46) BLMMEN1KMT2AGHSRALDH1A1
SCHEMBL7984108 0.86 KAT6A (0.50) MEN1KMT2AALDH1A1LMNAPOLB
SCHEMBL7984111 0.86 KAT6A (0.50) MEN1KMT2AALDH1A1LMNAPOLB
SCHEMBL7981747 0.84 MAPT (0.48) GHSRMAPT
SCHEMBL7981743 0.84 MAPT (0.48) GHSRMAPT
SCHEMBL9707019 0.84 ALDH1A1 (0.49) BLMMEN1KMT2AGHSRALDH1A1
SCHEMBL7982468 0.82 EGFR (0.43) MEN1KMT2AGHSRALDH1A1MAPT
SCHEMBL8648589 0.78 CYP2C19 (0.45) MEN1KMT2ABCAT1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6284912-B1 Process for synthesizing para-and/or meta-substituted cyanophenyalanine derivatives LG CHEMICAL, LTD. (KR) 2001-09-04 US disclosed
EP-1043309-A1 Process for synthesizing para-and/or meta-substituted cyanophenylalanine derivatives LG Chemical Ltd. (KR) 2000-10-11 EP disclosed