SCHEMBL6255018

SCHEMBL6255018

Cc1ccc(S(=O)(=O)NC(C)(Cc2ccc(O)cc2)C(=O)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 1/20 0.46
BLM P54132 1/20 0.46
LMNA P02545 3/20 0.43
POLB P06746 1/20 0.43
ALDH1A1 P00352 4/20 0.43
MAPT P10636 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 3/20 0.42
RAB9A P51151 1/20 0.42
KDM1A O60341 1/20 0.42
MEN1 O00255 2/20 0.41
EGFR P00533 3/20 0.41
ERBB2 P04626 3/20 0.41
TDP1 Q9NUW8 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
MMP1 P03956 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
MMP8 P22894 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6255022 1.00 GHSR (0.46) GHSRBLMLMNAPOLBALDH1A1
SCHEMBL7984128 0.89 BLM (0.48) GHSRBLMLMNAPOLBALDH1A1
SCHEMBL7984126 0.89 BLM (0.48) GHSRBLMLMNAPOLBALDH1A1
SCHEMBL7984352 0.85 BCHE (0.47) GHSRALDH1A1KMT2AKDM1ATDP1
SCHEMBL7981503 0.83 EGFR (0.43) GHSRALDH1A1MAPTKMT2AEGFR
SCHEMBL3926878 0.82 GHSR (0.42) GHSRBLMLMNAPOLBALDH1A1
SCHEMBL3926880 0.82 GHSR (0.42) GHSRBLMLMNAPOLBALDH1A1
SCHEMBL7984108 0.82 KAT6A (0.50) LMNAPOLBALDH1A1KMT2ARAB9A
SCHEMBL7984111 0.82 KAT6A (0.50) LMNAPOLBALDH1A1KMT2ARAB9A
SCHEMBL5996499 0.79 ALDH1A1 (0.48) LMNAPOLBALDH1A1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005057589-A2 MULTI-PURPOSE AUTOMATED RADIOTRACER SYNTHESIZER BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2005-06-23 WO disclosed