Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11696762 | 0.80 | KDM1A (0.54) | KDM1AMEN1KMT2AAKR1B1 | |
| SCHEMBL1101137 | 0.74 | KDM1A (0.59) | KDM1AMEN1KMT2AAKR1B1MAOB | |
| SCHEMBL30112838 | 0.74 | KDM1A (0.59) | KDM1AMEN1KMT2AAKR1B1MAOB | |
| SCHEMBL4784319 | 0.72 | KDM1A (0.46) | KDM1AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7755304 | 0.71 | KDM1A (0.45) | KDM1AMEN1KMT2A | |
| SCHEMBL5369769 | 0.71 | KDM1A (0.56) | KDM1AMEN1KMT2AAKR1B1MAOB | |
| SCHEMBL643388 | 0.71 | KDM1A (0.66) | KDM1AMEN1KMT2AAKR1B1MAOB | |
| SCHEMBL1273553 | 0.71 | KDM1A (0.66) | KDM1AMEN1KMT2AAKR1B1MAOB | |
| SCHEMBL4144872 | 0.71 | KDM1A (0.56) | KDM1AMEN1KMT2AAKR1B1MAOB | |
| SCHEMBL9396129 | 0.71 | KDM1A (0.56) | KDM1AMEN1KMT2AAKR1B1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001089453-A2 | DERIVATIVES OF 2-AMINOTETRALINS AND PHARMACEUTICAL ANALOGS THEREOF EXHIBITING DIFFERENTIAL CNS RECEPTOR ACTIVITY AND BEHAVIOR | WAYNE STATE UNIVERSITY (US) | 2001-11-29 | — | — | WO | disclosed |