SCHEMBL7984262

SCHEMBL7984262

CN(C(=O)[C@H](Cc1ccc(C#N)cc1)NC(=O)OC(C)(C)C)C1CCCC1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.51
CTSS P25774 10/20 0.48
CTSK P43235 9/20 0.48
CTSB P07858 2/20 0.47
CTSL P07711 1/20 0.47
CACNA1B Q00975 1/20 0.46
ACACB O00763 1/20 0.43
F2 P00734 4/20 0.42
ITGB3 P05106 1/20 0.42
ITGA2B P08514 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8109137 0.87 PTPN1 (0.47) PTPN1CTSSCTSKCTSBCTSL
SCHEMBL23742817 0.85 CTSS (0.56) PTPN1CTSSCTSKCTSBCTSL
SCHEMBL7015320 0.83 F2 (0.44) CTSSCTSKCTSBCTSLACACB
SCHEMBL7015327 0.83 F2 (0.44) CTSSCTSKCTSBCTSLACACB
SCHEMBL5155308 0.83 CTSS (0.54) PTPN1CTSSCTSKCTSBCTSL
SCHEMBL18920548 0.82 CTSS (0.53) PTPN1CTSSCTSKCTSBCTSL
SCHEMBL5151231 0.82 CTSS (0.53) PTPN1CTSSCTSKCTSBCTSL
SCHEMBL5155420 0.82 CTSS (0.53) PTPN1CTSSCTSKCTSBCTSL
SCHEMBL5150943 0.82 CTSS (0.53) PTPN1CTSSCTSKCTSBCTSL
SCHEMBL7983723 0.82 CTSS (0.55) CTSSCTSKCTSBCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6284912-B1 Process for synthesizing para-and/or meta-substituted cyanophenyalanine derivatives LG CHEMICAL, LTD. (KR) 2001-09-04 US disclosed
EP-1043309-A1 Process for synthesizing para-and/or meta-substituted cyanophenylalanine derivatives LG Chemical Ltd. (KR) 2000-10-11 EP disclosed