Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 12/20 | 0.55 |
| ▸ | CTSK | P43235 | 11/20 | 0.55 |
| ▸ | CTSB | P07858 | 4/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983717 | 1.00 | CTSS (0.55) | CTSSCTSKCTSBCTSLHDAC4 | |
| SCHEMBL21169918 | 0.90 | CTSS (0.52) | CTSSCTSKCTSBCTSLSCN9A | |
| SCHEMBL29923140 | 0.85 | FPR2 (0.65) | CTSSCTSKCTSBCTSLSCN9A | |
| SCHEMBL21144825 | 0.84 | CTSL (0.55) | CTSSCTSKCTSBCTSLSCN9A | |
| SCHEMBL18920632 | 0.84 | CTSL (0.55) | CTSSCTSKCTSBCTSLSCN9A | |
| SCHEMBL18930779 | 0.84 | CTSL (0.55) | CTSSCTSKCTSBCTSLSCN9A | |
| SCHEMBL9259839 | 0.83 | CTSS (0.63) | CTSSCTSKCTSBCTSL | |
| SCHEMBL18930492 | 0.83 | CTSS (0.63) | CTSSCTSKCTSBCTSL | |
| SCHEMBL9259835 | 0.83 | CTSS (0.63) | CTSSCTSKCTSBCTSL | |
| SCHEMBL21676598 | 0.82 | PIN1 (0.46) | CTSSCTSKCTSBCTSLSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284912-B1 | Process for synthesizing para-and/or meta-substituted cyanophenyalanine derivatives | LG CHEMICAL, LTD. (KR) | 2001-09-04 | — | — | US | disclosed |
| EP-1043309-A1 | Process for synthesizing para-and/or meta-substituted cyanophenylalanine derivatives | LG Chemical Ltd. (KR) | 2000-10-11 | — | — | EP | disclosed |