Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.34 |
| ▸ | MMP13 | P45452 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ESRRG | P62508 | 1/20 | 0.32 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984404 | 0.88 | PNMT (0.38) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7981681 | 0.83 | CTSL (0.37) | ADAMTS4MMP13RAB9APNMTNPC1 | |
| SCHEMBL7985056 | 0.81 | CA2 (0.47) | CXCR2RAB9ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30762664 | 0.81 | TYR (0.43) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22804105 | 0.81 | TYR (0.43) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9052782 | 0.81 | TYR (0.43) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3727529 | 0.81 | TYR (0.43) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7294513 | 0.80 | PNMT (0.41) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2551443 | 0.80 | CTSL (0.43) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2551437 | 0.80 | CTSL (0.43) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284912-B1 | Process for synthesizing para-and/or meta-substituted cyanophenyalanine derivatives | LG CHEMICAL, LTD. (KR) | 2001-09-04 | — | — | US | claimed |