Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985391 | 0.96 | HPGD (0.47) | ALDH1A1SMN1; SMN2HPGDGAAKMT2A | |
| SCHEMBL7974404 | 0.90 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2HPGDGAAKMT2A | |
| SCHEMBL7987767 | 0.87 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2HPGDGAAKMT2A | |
| SCHEMBL7974583 | 0.87 | GAA (0.59) | ALDH1A1SMN1; SMN2HPGDGAAKMT2A | |
| SCHEMBL7984460 | 0.85 | PARN (0.41) | ALDH1A1HPGDGAAKMT2AXBP1 | |
| Morpholine SCHEMBL7988796 | 0.82 | KMT2A (0.52) | ALDH1A1SMN1; SMN2HPGDGAAKMT2A | |
| SCHEMBL7985844 | 0.82 | GAA (0.52) | ALDH1A1HPGDGAA | |
| SCHEMBL7988590 | 0.81 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2HPGDGAAKMT2A | |
| SCHEMBL7987251 | 0.81 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2HPGDGAAKMT2A | |
| SCHEMBL7985399 | 0.81 | PARN (0.43) | ALDH1A1HPGDGAAKMT2AXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |