Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARN | O95453 | 1/20 | 0.41 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985399 | 0.96 | PARN (0.43) | PARNCNOT7HDAC3HDAC4HDAC1 | |
| SCHEMBL7974409 | 0.90 | PARN (0.45) | PARNCNOT7TSHRKMT2AALDH1A1 | |
| SCHEMBL7987774 | 0.87 | CNOT7 (0.46) | PARNCNOT7TSHRNPSR1ADORA2A | |
| SCHEMBL7974586 | 0.87 | GAA (0.52) | PARNCNOT7GAAMAPT | |
| SCHEMBL7984451 | 0.85 | ALDH1A1 (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7985633 | 0.82 | ADORA2A (0.54) | TSHRKMT2AADORA2AADORA1 | |
| SCHEMBL7985852 | 0.82 | TP53 (0.52) | GAAMAPT | |
| SCHEMBL7988597 | 0.81 | PARN (0.48) | PARNCNOT7KMT2AALDH1A1HPGD | |
| SCHEMBL7987255 | 0.81 | PARN (0.48) | PARNCNOT7ALDH1A1HPGDADORA1 | |
| SCHEMBL7985391 | 0.81 | HPGD (0.47) | KMT2AALDH1A1HPGDXBP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |