Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974404 | 0.91 | SMN1; SMN2 (0.49) | KMT2AHPGDSMN1; SMN2ALDH1A1GAA | |
| Morpholine SCHEMBL7991505 | 0.91 | KMT2A (0.55) | KMT2AHPGDSMN1; SMN2ALDH1A1GAA | |
| Morpholine SCHEMBL7984416 | 0.87 | KMT2A (0.52) | KMT2AHPGDSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL7985391 | 0.83 | HPGD (0.47) | KMT2AHPGDSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL7974583 | 0.83 | GAA (0.59) | KMT2AHPGDSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL7984451 | 0.82 | ALDH1A1 (0.46) | KMT2AHPGDSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL7974476 | 0.81 | GUSB (0.56) | KMT2AHPGDSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL7985844 | 0.78 | GAA (0.52) | HPGDALDH1A1GAATP53KDM4E | |
| SCHEMBL7988590 | 0.78 | ALDH1A1 (0.53) | KMT2AHPGDSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL7975265 | 0.78 | SMN1; SMN2 (0.61) | KMT2AHPGDSMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |