Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985450 | 0.95 | CNOT7 (0.48) | CNOT7RAB9ANPC1SMN1; SMN2MAOA | |
| SCHEMBL7984480 | 0.83 | CNOT7 (0.47) | CNOT7L3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7984469 | 0.83 | CNOT7 (0.54) | CNOT7SMN1; SMN2MAOAMAOBKMT2A | |
| SCHEMBL7974647 | 0.82 | CNOT7 (0.51) | CNOT7SMN1; SMN2RXFP1KMT2AACP1 | |
| SCHEMBL7973921 | 0.80 | ALDH1A1 (0.42) | CNOT7L3MBTL1RAB9ANPC1PKM | |
| SCHEMBL7988188 | 0.78 | CNOT7 (0.44) | CNOT7L3MBTL1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL7985875 | 0.78 | TP53 (0.48) | RXFP1LMNAMAPT | |
| SCHEMBL7985444 | 0.78 | CNOT7 (0.41) | CNOT7L3MBTL1RAB9ASMN1; SMN2MAOA | |
| SCHEMBL7985775 | 0.78 | CNOT7 (0.58) | CNOT7L3MBTL1RAB9ANPC1LTA4H | |
| SCHEMBL7988457 | 0.76 | PARN (0.42) | CNOT7SMN1; SMN2KMT2AACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |