Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 4/20 | 0.51 |
| ▸ | PARN | O95453 | 1/20 | 0.51 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PNP | P00491 | 2/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988188 | 0.93 | CNOT7 (0.44) | CNOT7PARNCXCR2SMN1; SMN2KMT2A | |
| SCHEMBL7974061 | 0.91 | CNOT7 (0.42) | CNOT7PARNCXCR2SMN1; SMN2KMT2A | |
| SCHEMBL7984880 | 0.91 | P2RX7 (0.46) | CNOT7PARNCXCR2SMN1; SMN2KMT2A | |
| SCHEMBL7988457 | 0.90 | PARN (0.42) | CNOT7PARNCXCR2SMN1; SMN2KMT2A | |
| SCHEMBL7974278 | 0.89 | CNOT7 (0.53) | CNOT7PARNCXCR2SMN1; SMN2KMT2A | |
| SCHEMBL7974312 | 0.88 | HPGD (0.45) | CNOT7PARNCXCR2SMN1; SMN2KMT2A | |
| SCHEMBL7984201 | 0.88 | ABCC8 (0.44) | CNOT7PARNCXCR2SMN1; SMN2KMT2A | |
| SCHEMBL7973921 | 0.88 | ALDH1A1 (0.42) | CNOT7PARNACP1ALDH1A1P2RX7 | |
| SCHEMBL7974857 | 0.87 | CNOT7 (0.52) | CNOT7PARNCXCR2SMN1; SMN2KMT2A | |
| SCHEMBL7984469 | 0.87 | CNOT7 (0.54) | CNOT7PARNCXCR2SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |